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Updated: Mar 31, 2026

Spontaneous Formation and Rearrangement of Artificial Lipid Nanotube Networks as a Bottom-Up Model for Endoplasmic Reticulum
Published on: January 22, 2019
Self-Organization of Quantum Rods Induced by Lipid Membrane Corrugations
Thomas Bizien1,2,3, Jean-Claude Ameline2, Kevin G Yager4
1Université de Rennes 1, CNRS UMR 6226, Institut des Sciences Chimiques de Rennes, Avenue du Général Leclerc, 35042 Rennes, France.
Abstract:
Self-organization of fluorescent nanoparticles, using biological molecules such as phospholipids to control assembly distances, is a promising method for creating hybrid nanostructures. We report here the formation of hybrid condensed phases made of anisotropic nanoparticles and phospholipids. Such structure formation is driven by electrostatic interaction between the nanoparticles and the phospholipids, and results in the formation of a 2D rectangular liquid crystal, as confirmed by high-resolution Small-Angle X-ray Scattering (SAXS). Moreover, we show that the fluorescent properties of the NPs are not modified by the self-assembly process.
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