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Clinical Microfluidic Chip Platform for the Isolation of Versatile Circulating Tumor Cells
Published on: October 13, 2023
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Surface engineering of macrophages with nucleic acid aptamers for the capture of circulating tumor cells
Shunsuke Sugimoto1, Rui Moriyama2, Takeshi Mori3
1Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, 3-3-35 Yamate-cho, Suita-shi, Osaka 564-8680, Japan. yasu.bmt@kansai-u.ac.jp.
Chemical Communications (Cambridge, England)
|October 16, 2015
Abstract:
In order to enhance the interactions between macrophages and cancer cells, thiol-terminated nucleic acid aptamers were immobilized on methacryloyl-functionalised carbohydrates of macrophages. The adhesion of cancer cells on the surface modified macrophages was significantly accelerated.
