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Related Experiment Videos

Magnetic resonance technology in human brain science: blueprint for a program based upon morphometry.

V S Caviness1, P A Filipek, D N Kennedy

  • 1Pediatric Neurology Service, Massachusetts General Hospital, Boston 02114.

Brain & Development
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

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Methods (San Diego, Calif.)·2009

Magnetic resonance imaging (MRI) offers unparalleled brain analysis. This review details MRI techniques for measuring brain volume, shape, and position, aiding in understanding brain diseases.

Area of Science:

  • Neuroimaging
  • Human Brain Science
  • Pathoanatomic Analysis

Background:

  • Magnetic resonance images (MRI) offer unprecedented detail in human brain analysis.
  • Existing pathoanatomic analysis methods lack the resolution of MRI.

Purpose of the Study:

  • To review MRI-based image analysis strategies and technologies.
  • To extract independent measures of human brain volume, shape, and position.
  • To correlate these parameters with behavioral and physiological measures.

Main Methods:

  • Review of MRI-based image analysis strategies.
  • Extraction of independent measures for brain volume, shape, and position.
  • Correlation with Positron Emission Tomography (PET) and in vivo spectroscopy data.

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Main Results:

  • MRI enables comprehensive analysis of human brain structure.
  • Independent measures of brain volume, shape, and position can be extracted.
  • These MRI-derived parameters correlate with behavioral and physiological data.

Conclusions:

  • MRI-based analysis provides novel insights into brain structure and function.
  • A coordinate program utilizing these methods has broad applications in human brain science.
  • This approach is valuable for studying the dynamic properties of human brain disease.