Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

446
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
446
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

322
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
322
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

973
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
973
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

490
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
490
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

654
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
654
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

686
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
686

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Translating Mechanistic Insights Into Action and Revealing New Pathways: Machine Learning Approaches in Heart Failure With Preserved Ejection Fraction.

Journal of the American Heart Association·2026
Same author

Right Ventricular Dysfunction and Adverse Clinical Outcomes in Peripartum Cardiomyopathy: A Meta-Analysis.

JACC. Advances·2025
Same author

Relationship of Lung Function and the Preserved Ratio Impaired Spirometry Pattern with Aortic and Left Ventricular Structure and Function on Magnetic Resonance Imaging: The Jackson Heart Study.

Lung·2025
Same author

The association of heart rate with adverse outcomes and recurrent heart failure hospitalization in peripartum cardiomyopathy.

Clinical research in cardiology : official journal of the German Cardiac Society·2025
Same author

Physio-Friendly Remission-Facilitating Pharmacotherapy (PRP) in Type 2 Diabetes.

JPMA. The Journal of the Pakistan Medical Association·2024
Same author

Headache in diabetes.

JPMA. The Journal of the Pakistan Medical Association·2024

Related Experiment Video

Updated: Mar 31, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K

Lupus nephritis: an update.

Tasnim F Imran1, Frederick Yick2, Suneet Verma2,3

  • 1Department of Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, 185 South Orange Avenue, Newark, NJ, 07103, USA. imranta@njms.rutgers.edu.

Clinical and Experimental Nephrology
|October 17, 2015
PubMed
Summary
This summary is machine-generated.

Lupus nephritis (LN) is a severe kidney inflammation in systemic lupus erythematosus (SLE) patients. Reviewing pathogenesis and therapies, including immunosuppressants and biologics, is crucial for better outcomes.

Keywords:
Lupus nephritisRenal lupusSystemic lupus erythematosus

More Related Videos

Murine Bilateral Renal Lymphadenectomy
06:20

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

148
Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

1.1K

Related Experiment Videos

Last Updated: Mar 31, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

3.6K
Murine Bilateral Renal Lymphadenectomy
06:20

Murine Bilateral Renal Lymphadenectomy

Published on: December 30, 2025

148
Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

1.1K

Area of Science:

  • Nephrology
  • Immunology
  • Rheumatology

Background:

  • Lupus nephritis (LN) is a critical complication of systemic lupus erythematosus (SLE), significantly impacting patient prognosis.
  • Pathogenesis involves genetic and environmental factors, leading to glomerular and tubulointerstitial kidney disease.
  • Untreated LN carries high morbidity and mortality, necessitating timely diagnosis and management.

Purpose of the Study:

  • To review the pathogenesis, classification, and clinical manifestations of lupus nephritis.
  • To discuss established and emerging therapeutic strategies for proliferative and membranous lupus nephritis.
  • To highlight the importance of optimizing risk factors and immunosuppressive regimens.

Main Methods:

  • Literature review of lupus nephritis pathogenesis and treatment.
  • Analysis of renal biopsy findings for guiding therapeutic decisions.
  • Evaluation of current and novel immunosuppressive and biologic therapies.

Main Results:

  • Cyclophosphamide and corticosteroid regimens have improved survival, but relapse rates remain high.
  • Renin-angiotensin receptor blockade is vital for managing proteinuria and hypertension.
  • Biologic therapies like Belimumab and Rituximab show promise in managing refractory cases.

Conclusions:

  • Optimizing risk factors and employing appropriate immunosuppressive therapy are key to managing lupus nephritis.
  • Established treatments improve outcomes, yet optimal therapeutic strategies are still evolving.
  • Further research into novel agents and combination therapies is essential for improving long-term prognosis in LN patients.