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Related Experiment Video

Updated: Mar 31, 2026

Plasmonic Trapping and Release of Nanoparticles in a Monitoring Environment
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Single nanoparticle plasmonic sensors.

Manish Sriram1,2,3, Kelly Zong4,5,6, S R C Vivekchand7,8,9

  • 1School of Chemistry, The University of New South Wales, Sydney 2052, Australia. m.sriram@unsw.edu.au.

Sensors (Basel, Switzerland)
|October 17, 2015
PubMed
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This summary is machine-generated.

Single plasmonic nanoparticle sensors enable single-molecule biosensing by analyzing localized surface plasmon resonances. This review covers synthesis, functionalization, and detection techniques for advanced biosensing applications.

Area of Science:

  • Plasmonics
  • Nanotechnology
  • Biosensing

Background:

  • Optical sensors utilizing plasmonic nanomaterials enable biosensing at the single plasmonic particle level.
  • Single nanoparticle sensors offer single-molecule analysis of biochemical interactions, surpassing ensemble measurement information yields.

Purpose of the Study:

  • To introduce the fundamental concepts of single nanoparticle sensing.
  • To explore the influence of material, shape, and size on localized surface plasmon resonances.
  • To review synthesis, purification, functionalization, and detection techniques for plasmonic nanoparticle-based biosensors.

Main Methods:

  • Discussion of plasmonic nanomaterial properties and their dependence on physical characteristics.
  • Overview of synthetic approaches including citrate reduction, seed-mediated, and seedless growth for gold and silver nanostructures.
Keywords:
metal nanoparticlesoptical sensorssensorssingle molecule detectionsurface plasmons

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  • Exploration of nanoparticle purification, functionalization, and sensing surface fabrication.

    • Main Results:

    • Plasmonic nanomaterials exhibit size- and shape-dependent localized surface plasmon resonances crucial for sensing.
    • Various synthetic methods allow for tunable synthesis of diverse gold and silver nanostructures.
    • Advancements in detection, spectroscopy, and application highlight the potential of single nanoparticle biosensing.

    Conclusions:

    • Single plasmonic nanoparticle sensing provides a powerful platform for high-information-yield biochemical analysis.
    • The review consolidates knowledge on synthesis, characterization, and application of these advanced biosensors.
    • Future developments in detection and spectroscopy will further enhance the capabilities of single nanoparticle biosensing.