[Related factors of hemodynamic damage after carotid artery stenting]
Jin-tao Han1, Hai-yan Zhao2, Xuan Li1
1Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing 100191, China.
Insights
Carotid artery stenting can cause hemodynamic damage. Eccentric and calcified plaques are key factors linked to this damage, influencing patient outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Cardiovascular Research
Background:
- Carotid artery stenting (CAS) is a common procedure for treating carotid artery stenosis.
- Hemodynamic damage, including hypotension, can occur post-CAS, necessitating identification of predictive factors.
- Understanding these factors is crucial for improving patient safety and procedural success rates.
Purpose of the Study:
- To identify and analyze the correlation factors associated with hemodynamic damage following carotid artery stenting.
- To investigate the relationship between lesion characteristics and hemodynamic complications after CAS.
Main Methods:
- Retrospective analysis of 66 patients (71 lesions) who underwent CAS.
- Statistical analysis, including single-factor and multiple-factor analyses, to determine correlations.
- Evaluation of factors such as lesion distance from bifurcation, plaque distribution, plaque character, and post-dilation.
Main Results:
- Hemodynamic damage occurred in 32.4% of patients, with 11.3% experiencing hypotension.
- Single-factor analysis identified lesion distance, plaque distribution, plaque character, and post-dilation as significant factors.
- Multiple-factor analysis revealed eccentric plaque (P=0.0153) and calcified plaque (P=0.0097) as independent predictors of hemodynamic damage.
Conclusions:
- The distance between the carotid bifurcation and the lesion, eccentric plaque morphology, and calcified plaque characteristics are significant correlation factors for hemodynamic damage after CAS.
- These findings can aid in risk stratification and procedural planning for patients undergoing CAS.
Objective:
To analyze correlation factors of hemodynamic damage after carotid artery stenting.
Methods:
In this study, 66 cases (71 lesions) who undertook carotid artery stenting were collected and the correlation factors of hemodynamic damage were analyzed.
Results:
Hemodynamic damage emerged in 23 cases (32.4%), of which, 11.3% developed hypotension. The distance between bifurcation and lesions (P=0.0020), plaque distribution (P=0.0002), plaque character (P=0.0019), post-dilation (P=0.0026) were associated with hemodynamic damage by single factor analysis. However, only eccentric plaque (P=0.0153) and calcified plaque (P=0.0097) were associated with hemodynamic damage by multiple factors analysis. All the patients could reach stable circulation by drugs during operation, and no cerebral ischemic events (transient ischemic attack or stroke) and cardiovascular ischemic events happened.
Conclusion:
The distance between bifurcation and lesions, eccentric plaques, calcified plaques are correlation factors of hemodynamic damage.
