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Related Concept Videos

Urinary Bladder01:23

Urinary Bladder

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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
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The Micturition Reflex01:26

The Micturition Reflex

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Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Disorders of the Urinary System01:20

Disorders of the Urinary System

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The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
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Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Updated: Mar 31, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
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Underactive Bladder in Older Adults.

Yao-Chi Chuang1, Mauricio Plata2, Laura E Lamb3

  • 1Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chung Shan Medical University Institute of Medicine, Kaohsiung, Taiwan.

Clinics in Geriatric Medicine
|October 18, 2015
PubMed
Summary
This summary is machine-generated.

Underactive bladder (UAB) affects millions, causing voiding difficulties and infections. Currently, no effective treatments exist for UAB, highlighting the need for further research into its causes and therapies.

Keywords:
AgingOveractive bladderUnderactive bladderUrinary incontinence

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Area of Science:

  • Geriatric Medicine
  • Urology
  • Public Health

Background:

  • Underactive bladder (UAB) is a prevalent condition affecting millions, often overlooked compared to overactive bladder.
  • UAB can lead to significant health complications, including urinary tract infections and potential institutionalization.

Purpose of the Study:

  • To provide a comprehensive overview of underactive bladder (UAB) specifically in the older adult population.
  • To discuss the current understanding of UAB's prevalence, risk factors, etiology, diagnostic methods, and available treatments.

Main Methods:

  • Literature review and synthesis of existing research on underactive bladder.
  • Analysis of prevalence data, predisposing factors, and etiological theories.
  • Examination of current clinical investigations and therapeutic approaches.

Main Results:

  • Underactive bladder (UAB) affects an estimated 20 million Americans, posing challenges in bladder emptying.
  • Predisposing factors, causes, and clinical presentations of UAB in older adults are detailed.
  • No consistently effective therapies are currently available for underactive bladder.

Conclusions:

  • Underactive bladder (UAB) is a significant health issue in older adults with serious consequences.
  • The lack of effective treatments underscores the urgent need for research into UAB pathogenesis.
  • Further investigation is required to develop targeted and effective therapies for underactive bladder.