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Updated: Mar 31, 2026

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
Comorbidities in Psoriatic Arthritis.
1Department of Rheumatic and Immunologic Diseases, Clinical Outcomes Research, Arthritis and Musculoskeletal Center, Cleveland Clinic, Desk A50, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Psoriatic arthritis (PsA) patients frequently experience comorbidities like cardiovascular disease and diabetes. Recognizing these associated conditions is crucial for effective PsA management and improved patient outcomes.
Area of Science:
- Rheumatology and Immunology
- Internal Medicine
- Public Health
Background:
- Psoriatic arthritis (PsA) is increasingly recognized as a systemic inflammatory disease.
- Epidemiologic data suggest a higher prevalence of comorbidities in PsA patients than anticipated.
- These comorbidities can significantly impact disease course and patient prognosis.
Purpose of the Study:
- To review and discuss the common comorbidities associated with psoriatic arthritis.
- To highlight the importance of identifying these comorbidities for optimal clinical management.
- To inform healthcare providers about the impact of comorbidities on treatment decisions in PsA.
Main Methods:
- Review of existing epidemiologic studies and clinical literature on psoriatic arthritis comorbidities.
- Synthesis of information regarding the prevalence and types of associated conditions.
- Discussion of the clinical implications for patient care and management strategies.
Main Results:
- PsA is frequently associated with a range of comorbidities.
- Commonly identified comorbidities include cardiovascular disease, metabolic syndrome, obesity, diabetes, fatty liver disease, inflammatory bowel disease, ophthalmic disease, kidney disease, osteoporosis, depression, and anxiety.
- These conditions occur more often than expected in the PsA population.
Conclusions:
- Awareness of comorbidities is essential for healthcare providers managing PsA patients.
- Identification and management of associated conditions are critical for optimizing treatment outcomes.
- A comprehensive approach addressing both PsA and its comorbidities is necessary for holistic patient care.
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