Candidiasis

C. albicans and its related species have become major nosocomial causes of morbidity and mortality in the immunocompromised and in other severely ill patients. Diagnosis of the severe forms of the disease remains difficult and depends on the basis of a composite of clinical findings. Treatment for most forms of severe Candida infections remains amphotericin B despite its toxicities. Until more effective prevention of the disease becomes feasible, Candida infections are likely to increase in frequency as major iatrogenic problems.