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Candidiasis.

M A Crislip1, J E Edwards

  • 1Harbor/UCLA Medical Center, Torrance.

Infectious Disease Clinics of North America
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

Candida albicans infections are a growing threat in hospitals, especially for vulnerable patients. Current diagnostic and treatment methods for severe candidiasis are limited, posing significant challenges.

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Hospital Epidemiology

Background:

  • Candida albicans and related species are significant causes of hospital-acquired infections.
  • These infections lead to increased morbidity and mortality, particularly in immunocompromised and critically ill individuals.

Purpose of the Study:

  • To highlight the challenges in diagnosing severe Candida infections.
  • To discuss current treatment strategies and their limitations.

Main Methods:

  • Clinical findings are primarily used for diagnosis.
  • Treatment relies heavily on amphotericin B.

Main Results:

  • Diagnosis of severe Candida infections is challenging and relies on a combination of clinical signs.
  • Amphotericin B remains the primary treatment despite its known toxicities.

    • Conclusions:

    • Candida infections are likely to increase due to iatrogenic factors.
    • Effective prevention strategies are needed to combat the rising incidence of these infections.