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Updated: Mar 31, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
Association of Systemic Anaplastic Large Cell Lymphoma and Active Toxoplasmosis in a Child
Shirin Sayyahfar1, Abdollah Karimi2, Atoosa Gharib3
1Department of Paediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, IR Iran.
Introduction:
Anaplastic large cell lymphoma is a subset of non-Hodgkin lymphoma and an unusual disease in children.
Case Presentation:
Herein we have reported a 7- year- old girl with a large necrotic skin ulcer on the chest caused by systemic form of anaplastic large-cell lymphoma and simultaneous active toxoplasmosis diagnosed by PCR on lymph node specimen. There were few reports showing a role for toxoplasma infection to cause some malignancies such as lymphoma in adults.
Conclusions:
Based to our knowledge, this has been the first report of simultaneous systemic anaplastic large cell lymphoma and active toxoplasmosis, documented by positive PCR on tissue biopsy in a child. This case report has suggested more attention to the accompanying Toxoplasma gondii infection as a probable cause of some types of lymphomas.
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