Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

46
The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
46
Glycocalyx and its Functions01:14

Glycocalyx and its Functions

10.4K
The glycocalyx is a carbohydrate-rich, fuzzy-appearing layer on the outer surface of the cell membrane. It is highly hydrophilic, because of this it attracts large amounts of water to the cell's surface. This aids the cell's interaction with the watery environment and also helps it to obtain substances dissolved in the water. It is also important for cell identification, self/non-self determination, and embryonic development and is used in cell-to-cell attachments to form tissues.
10.4K
Colonisation of Pathogens01:25

Colonisation of Pathogens

35
Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...
35
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

1.8K
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
1.8K
Physiology of Enteric Nervous System and Gut Health01:05

Physiology of Enteric Nervous System and Gut Health

1.3K
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
1.3K
Cross-reactivity00:42

Cross-reactivity

33.8K
Overview
33.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening of lactic acid bacteria and comparative inoculated fermentation to evaluate strain performance in Korean-style spicy cabbage.

Journal of the science of food and agriculture·2026
Same author

Construction of dual-enzyme hybrid nanoflowers by protein self-assembly and biomineralization for efficient biosynthesis of d-tagatose.

Bioresource technology·2026
Same author

Remodeling of phenolic compounds from celery pulp driven by Lactobacillus plantarum NCU116 fermentation: insights from omics, targeted quantification, and microstructural imaging.

Food research international (Ottawa, Ont.)·2026
Same author

Bioactive Substances Characterization in Probiotic-Fermented Guava (Psidium guajava L.) Juice and Systematic Evaluation of its Anti-Hyperglycemic Activity.

Plant foods for human nutrition (Dordrecht, Netherlands)·2026
Same author

Lactic acid bacteria fermentation improves the physicochemical properties, bioactivity, and metabolic profiles of lychee pulp.

Food chemistry: X·2026
Same author

Glucan versus pectin: Structurally distinct polysaccharides differentially protect against ethanol-induced gastric injury via the gut microbiota-metabolite axis.

International journal of biological macromolecules·2026

Related Experiment Video

Updated: Mar 31, 2026

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
08:24

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

Published on: May 2, 2018

20.7K

Interaction between gut immunity and polysaccharides.

Xiaojun Huang1, Shaoping Nie1, Mingyong Xie1

  • 1a State Key Laboratory of Food Science and Technology , Nanchang University , Nanchang , P. R. China.

Critical Reviews in Food Science and Nutrition
|October 20, 2015
PubMed
Summary

Dietary polysaccharides promote gut health by balancing gut microbiota and supporting immune function. These compounds enhance beneficial bacteria and stimulate immune cells to combat diseases, highlighting their role in intestinal well-being.

Keywords:
Gut microbiotagut-associated lymphoid tissuesinflammatory bowel diseasepolysaccharides

More Related Videos

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

5.2K
Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches
08:25

Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches

Published on: November 21, 2018

14.4K

Related Experiment Videos

Last Updated: Mar 31, 2026

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
08:24

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

Published on: May 2, 2018

20.7K
An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

5.2K
Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches
08:25

Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches

Published on: November 21, 2018

14.4K

Area of Science:

  • Microbiology
  • Immunology
  • Nutrition Science

Background:

  • The human gut hosts a diverse microbial ecosystem crucial for health.
  • Gut-associated lymphoid tissues form the largest mucosal immune system, vital for host immunity.
  • Maintaining gut homeostasis involves both microbiota balance and immune tissue function.

Purpose of the Study:

  • To explore the relationship between gut immunity and host health.
  • To summarize the impacts of dietary polysaccharides on intestinal health.
  • To elucidate the immunomodulatory mechanisms of polysaccharides.

Main Methods:

  • Review of experimental and clinical evidence on dietary polysaccharides.
  • Analysis of microbiota composition and gut pH regulation.
  • Investigation of immune cell stimulation in gut-associated lymphoid tissues.

Main Results:

  • Dietary polysaccharides can improve the ratio of probiotics in the gut.
  • These compounds regulate the intestinal microenvironment, including decreasing gut pH.
  • Polysaccharides stimulate macrophages and lymphocytes in gut tissues, aiding disease defense.

Conclusions:

  • Dietary polysaccharides offer significant benefits for intestinal health.
  • They play a key role in modulating gut immunity through microbiota and immune cell interactions.
  • Understanding these mechanisms can inform strategies for disease prevention and treatment.