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Related Experiment Video

Updated: Mar 31, 2026

Establishment of Central Cord Syndrome Model in C57BL/6J Mouse

Establishment of Central Cord Syndrome Model in C57BL/6J Mouse

Published on: September 8, 2023

Spinal cord involvement in Behçet's disease.

Hyung Seok Lee¹, Do Young Kim², Ha Young Shin³

¹Department of Neurology, Yonsei University College of Medicine, Republic of Korea.

Multiple Sclerosis (Houndmills, Basingstoke, England)

|October 21, 2015

Summary

Spinal cord involvement in Behçet

Keywords:

Behçet’s disease longitudinally extensive transverse myelitis neuro-Behçet’s disease neuromyelitis optica serum anti-aquaporin-4 antibody spinal cord

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Area of Science:

Neurology
Immunology
Rheumatology

Background:

Spinal cord involvement in Behçet's disease is infrequently studied.
Understanding neurological manifestations is crucial for patient management.

Purpose of the Study:

To characterize spinal cord involvement in Behçet's disease.
Evaluate clinical, laboratory, and MRI findings.

Main Methods:

Retrospective review of 10 spinal cord involvement cases in 7 Behçet's disease patients.
Analysis of clinical, cerebrospinal fluid, and MRI data.

Main Results:

Median age of onset was 32 years; two patients had progressive disease.
Lesions often exceeded three vertebrae (8/10 cases).
Cerebrospinal fluid showed mild-moderate pleocytosis/elevated protein; anti-aquaporin-4 antibodies were negative.

Conclusions:

Longitudinally extensive transverse myelitis is characteristic of Behçet's disease spinal cord involvement.
MRI findings and clinical course provide diagnostic clues.