Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early

John M Kane1, Delbert G Robinson1, Nina R Schooler1

  • 1From the Division of Psychiatry Research, Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, N.Y.; the Departments of Psychiatry and of Molecular Medicine, Hofstra North Shore-Long Island Jewish School of Medicine, and the Department of Mathematics, Hofstra University, Hempstead, N.Y.; the Feinstein Institute for Medical Research, Manhasset, N.Y.; the Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, N.Y.; the Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, N.Y.; the Departments of Occupational Therapy, Psychiatry, and Psychology, Center for Psychiatric Rehabilitation, Boston University, Boston; the Departments of Psychology and of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, N.C.; the School of Psychology, Australian Catholic University, Melbourne; the Department of Psychiatry, Yale Medical School, and Yale School of Public Health, New Haven, Conn.; the Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Calgary, Alta., Canada; the Geisel School of Medicine, Dartmouth College, Lebanon, N.H.; the Bureau of Behavioral Health, New Hampshire Department of Health and Human Services, Concord, N.H.; Nathan Kline Institute, Orangeburg, N.Y.; Minnesota Center for Chemical and Mental Health, School of Social Work, University of Minnesota, St. Paul; the Semel Institute of Neuroscience and Human Behavior, UCLA, Los Angeles; University of Texas Southwestern Medical Center, Dallas; the Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Tex.; and the Division of Services and Intervention Research, NIMH, Rockville, Md.

Summary

NAVIGATE, a team-based treatment for first-episode psychosis, improved quality of life and clinical outcomes compared to community care. Early intervention is key, with better results for those with shorter durations of untreated psychosis.

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