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Simple renal cyst and renal dysfunction: A pilot study using dimercaptosuccinic acid renal Scan
Taekmin Kwon1, Bumjin Lim1, Dalsan You1
1Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Nephrology (Carlton, Vic.)
|October 21, 2015
Summary
Large renal cysts can impair kidney function. A study found over 60% of patients with large renal cysts showed decreased function in the affected kidney, highlighting a significant association.
Area of Science:
- Nephrology
- Urology
- Radiology
Background:
- The relationship between renal cysts and kidney dysfunction is not well-established.
- Unilateral, large, simple renal cysts are common findings.
Purpose of the Study:
- To evaluate the association between unilateral, large, simple renal cysts and renal dysfunction.
- To assess the deterioration of renal function in patients with these cysts.
Main Methods:
- Fifty patients with unilateral simple renal cysts (≥ 4 cm) and 50 kidney donors were enrolled.
- Dimercaptosuccinic acid (DMSA) renal scans were used to calculate split renal function.
- Clinical factors associated with decreased renal function in the cyst group were analyzed.
Main Results:
- Patients with renal cysts were older and more likely to have hypertension.
- Over 60% of patients with renal cysts showed decreased relative renal function in the cystic kidney.
- Cystic kidney units had significantly lower relative renal function compared to contralateral units.
Conclusions:
- A significant proportion of unilateral, large, simple renal cysts are associated with decreased relative renal function.
- Decreased renal function in cystic kidneys was linked to higher serum uric acid and RENAL complexity.
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