Related Experiment Video

Updated: Mar 31, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.7K

Sleep disturbances and mild cognitive impairment: A review

Renata Alves Pachota Chaves da Silva1

  • 1Instituto do Sono, Sao Paulo, SP, Brazil.

Sleep Science (Sao Paulo, Brazil)
|October 21, 2015
PubMed
Abstract

Insights

Sleep disturbances are common in mild cognitive impairment (MCI), occurring more frequently than in normal cognition. Early identification and treatment of sleep problems in MCI patients are crucial for preserving cognitive function.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Geriatrics

Background:

  • Mild cognitive impairment (MCI) represents a transitional phase between normal cognition and dementia.
  • Sleep disturbances are increasingly recognized as a significant factor in cognitive health.

Purpose of the Study:

  • To analyze the prevalence and characteristics of sleep disturbances in individuals diagnosed with MCI.
  • To understand the relationship between sleep problems and cognitive decline in the context of MCI.

Main Methods:

  • A comprehensive literature review was conducted.
  • Studies comparing sleep disturbances in MCI patients versus cognitively normal individuals were analyzed.

Main Results:

  • Nighttime behavioral disturbances were found to be significantly more common in MCI patients (18.3-45.5%) compared to the normal cognitive population (10.9-23.3%).
  • Sleep disturbances are prevalent in individuals with MCI.

Conclusions:

  • Sleep disturbances are prevalent and predictive of cognitive decline, particularly in older adults and those with neurodegenerative disorders.
  • Identifying and treating sleep problems in MCI patients is essential for cognitive preservation.
  • MCI subjects experiencing sleep disturbances require closer monitoring for early dementia signs.
Keywords:
DementiaElderlyMild cognitive impairmentSleep apneaSleep disturbance

More Related Videos

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

8.2K
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

6.2K

Related Concept Videos

Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
3.3K
Insomnia01:27

Insomnia

Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
588
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
1.3K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
847
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
2.5K
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
2.0K