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Updated: May 22, 2026

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REM Sleep Behavior Disorder as a Key Predictor of Cognitive Decline: Insights from a Narrative Review

Faezeh Khorshidian1

  • 1Department of Psychiatry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Sleep Science (Sao Paulo, Brazil)
|May 21, 2026
PubMed
Summary

Rapid eye movement (REM) sleep behavior disorder (RBD) signals future synucleinopathies like Parkinson's disease. Early identification via neuropsychological testing, imaging, and biomarkers is crucial for managing cognitive decline.

Keywords:
Parkinson diseasealpha-synucleindementia with Lewy bodiesneurodegenerative diseasesparasomniaspolysomnography

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