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Related Experiment Video

Updated: Mar 31, 2026

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
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Mental status changes and stroke.

S R Benbadis1, C A Sila, R L Cristea

  • 1From the Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH, U.S.A.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|October 22, 2015
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Summary
This summary is machine-generated.

Stroke is a rare cause of acute confusional state, accounting for only 7% of cases. A thorough neurological examination is highly effective in ruling out stroke and guiding imaging decisions.

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Area of Science:

  • Neurology
  • Neuroscience
  • Internal Medicine

Background:

  • Acute confusional state (ACS) is a common neurological presentation.
  • Determining the etiology of ACS is crucial for timely and appropriate management.
  • Stroke is a potential, though often overlooked, cause of ACS.

Purpose of the Study:

  • To determine the frequency of stroke as a cause of ACS.
  • To evaluate the utility of computed tomography (CT) in diagnosing stroke in ACS patients.
  • To assess the diagnostic value of neurological examination in this context.

Main Methods:

  • Retrospective analysis of 127 neurology consultations for acute, isolated mental status changes.
  • Review of patient data to identify stroke as the cause of ACS.
  • Correlation of neurological examination findings with stroke diagnosis and CT results.

Main Results:

  • Stroke was identified as the cause in 7% (9/127) of ACS cases (1 subarachnoid hemorrhage, 8 ischemic strokes).
  • 66% (6/9) of stroke patients with isolated mental symptoms had focal neurological deficits.
  • Only 2.7% (3/109) of patients without focal findings were diagnosed with stroke.

Conclusions:

  • Stroke is an uncommon cause of acute confusional state.
  • Neurological examination is a reliable tool for excluding stroke in ACS patients, with a 97% negative predictive value.
  • CT is useful in selected ACS patients with suspected stroke, particularly those with focal neurological deficits.