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Updated: Mar 31, 2026
Formulation and Acoustic Modulation of Optically Vaporized Perfluorocarbon Nanodroplets
Published on: July 16, 2021
Drug-Loaded Perfluorocarbon Nanodroplets for Ultrasound-Mediated Drug Delivery
1Department of Bioengineering, University of Utah, 36 South Wasatch Drive, Room, 3100, Salt Lake City, UT, 84112, USA. natasha.rapoport@utah.edu.
Abstract:
The interaction of nanoparticles with directed energy is a novel application in targeted drug delivery. This chapter focuses on perfluorocarbon nanoemulsions, whose action in drug delivery depends on the ultrasound-triggered phase shift from liquid to gaseous state. These nanoemulsions have great potential for unloading encapsulated drugs at a desired time and location in the body in response to directed ultrasound. In addition, they actively alter their nano-environment for enhancing drug transport through various biological barriers to sites of action, which significantly enhances therapeutic outcome.
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