Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.9K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.9K
Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

6.6K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
6.6K
Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

6.0K
The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
6.0K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

70.3K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
70.3K
Adrenergic Agonists: Therapeutic Uses01:30

Adrenergic Agonists: Therapeutic Uses

2.2K
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
2.2K
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

993
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
993

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of learning and training in supporting emotional resilience in security forces.

Frontiers in psychology·2026
Same author

Copeptin (Not Only) in Water and Sodium Disorders.

Acta medica (Hradec Kralove)·2026
Same author

Selected case reports from the practice of a clinical pharmacist in the field of pneumology.

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti·2025
Same author

Socioeconomic disparities in changes to preterm birth and stillbirth rates during the first year of the COVID-19 pandemic: a study of 21 European countries.

European journal of public health·2024
Same author

Hand2 Immunohistochemistry in the Diagnosis of Paragangliomas and Other Neuroendocrine Neoplasms.

Endocrine pathology·2024
Same author

Developing and testing a protocol using a common data model for federated collection and analysis of national perinatal health indicators in Europe.

Open research Europe·2023

Related Experiment Video

Updated: Mar 31, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.5K

[Adrenal insufficiency].

Filip Gabalec, Jan Čáp

    Vnitrni Lekarstvi
    |October 22, 2015
    PubMed
    Summary

    Adrenal insufficiency, a critical condition, requires careful diagnosis and treatment. This paper reviews diagnostic methods, corticosteroid therapy adjustments, and hormone replacement strategies, including novel options.

    Area of Science:

    • Endocrinology
    • Internal Medicine

    Background:

    • Adrenal insufficiency is a serious endocrine disorder with significant morbidity and mortality.
    • Accurate diagnosis and appropriate management are crucial for patient outcomes.

    Purpose of the Study:

    • To provide a comprehensive overview of adrenal insufficiency diagnostics and therapeutics.
    • To discuss the evolving landscape of corticosteroid and hormone replacement therapies.

    Main Methods:

    • Review of current literature on adrenal insufficiency.
    • Analysis of diagnostic testing limitations and dynamic testing protocols.
    • Evaluation of corticosteroid de-escalation and hormone substitution strategies.

    Main Results:

    • Differential diagnostics and dynamic testing have specific limitations.

    More Related Videos

    Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
    04:33

    Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions

    Published on: March 12, 2019

    8.7K
    Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
    08:02

    Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

    Published on: April 25, 2016

    10.2K

    Related Experiment Videos

    Last Updated: Mar 31, 2026

    A Novel Method: Super-selective Adrenal Venous Sampling
    06:08

    A Novel Method: Super-selective Adrenal Venous Sampling

    Published on: September 15, 2017

    24.5K
    Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions
    04:33

    Primary Culture of Rat Adrenocortical Cells and Assays of Steroidogenic Functions

    Published on: March 12, 2019

    8.7K
    Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
    08:02

    Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

    Published on: April 25, 2016

    10.2K
  • Optimizing corticosteroid therapy and hormone replacement is key.
  • Emerging therapeutic options offer new avenues for management.

    • Conclusions:

    • Effective management of adrenal insufficiency relies on precise diagnostics and tailored therapy.
    • Current and future replacement strategies aim to improve patient well-being and reduce treatment burdens.