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[Semen allergy].

J-P Allam1, G Haidl2, N Novak2

  • 1Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland. jean-pierre.allam@ukb.uni-bonn.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|October 23, 2015
PubMed
Summary
This summary is machine-generated.

Semen allergy, a type I hypersensitivity reaction, causes local or systemic allergic responses to seminal plasma (SP) allergens. Diagnosis involves symptom absence with condom use, skin prick tests, and IgE determination, with treatment options including desensitization.

Keywords:
AllergensAnaphylaxisDesensitization, immunologicEjaculationInsemination

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Area of Science:

  • Reproductive immunology
  • Allergy and immunology

Context:

  • Semen allergy, a type I hypersensitivity reaction, presents with local or systemic symptoms upon exposure to seminal plasma (SP).
  • Accurate incidence and prevalence data are lacking, complicating epidemiological understanding.
  • Allergens are identified as SP-typical (e.g., prostate-specific antigen) or SP-atypical (e.g., accumulated food or medication allergens).

Purpose:

  • To review the characteristics, diagnosis, and management of semen allergy.
  • To identify known allergens and diagnostic criteria.
  • To outline treatment strategies for affected individuals.

Summary:

  • Semen allergy involves IgE-mediated reactions to seminal plasma components, manifesting as contact dermatitis, urticaria, angioedema, or anaphylaxis.
  • Diagnosis relies on symptom correlation with intercourse, symptom resolution with condom use, skin prick testing, and specific IgE measurement.
  • Management includes allergen avoidance, use of washed sperm for assisted reproduction, and potential desensitization therapies.

Impact:

  • Provides a comprehensive overview of semen allergy for clinicians and researchers.
  • Highlights diagnostic challenges and therapeutic options, improving patient care.
  • Emphasizes the distinction between SP-typical and SP-atypical allergens, aiding etiological understanding.