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Updated: Mar 31, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
A Rare Cause of Reversible Renal Hemosiderosis
Rima Abou Arkoub1, Don Wang2, Deborah Zimmerman3
1Division of nephrology, The Ottawa Hospital, Ottawa, ON, Canada K1H 7W9.
Abstract:
Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology, causes, and prognosis of acute tubular injury from hemosiderosis.
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