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PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
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CacyBP/SIP--Structure and variety of functions

Agnieszka M Topolska-Woś1, Walter J Chazin2, Anna Filipek1

  • 1Nencki Institute of Experimental Biology, Warsaw, Poland.

Biochimica Et Biophysica Acta
|October 24, 2015
PubMed
Summary

Calcyclin-Binding Protein and Siah-1 Interacting Protein (CacyBP/SIP) is a versatile protein involved in numerous cellular functions. Its altered levels and localization link it to cancer and neurodegenerative diseases, highlighting its therapeutic potential.

Keywords:
CacyBP/SIPCytoskeletal reorganizationDifferentiationPost-translational modificationsProliferation and tumorigenesisProtein structure

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