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Related Concept Videos

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism
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Tuberous sclerosis complex coexistent with hippocampal sclerosis.

Min Lang1, Richard A Prayson1

  • 1Case Western Reserve University School of Medicine and Department of Anatomic Pathology, L25, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 27, 2015
PubMed
Summary

This study details a rare case of co-existing tuberous sclerosis and hippocampal sclerosis in a pediatric patient with intractable epilepsy. Surgical intervention led to seizure freedom, highlighting a rare epilepsy etiology.

Area of Science:

  • Neurology
  • Epileptology
  • Pediatric Neurology

Background:

  • Tuberous sclerosis (TSC) and hippocampal sclerosis (HS) are distinct neurological conditions often linked to intractable epilepsy.
Keywords:
Cortical tuberEpilepsyFocal cortical dysplasiaHippocampal sclerosisTuberous sclerosis

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  • The co-occurrence of TSC and HS is exceptionally rare, with limited documented cases.
  • Intractable epilepsy in infants necessitates thorough investigation into underlying pathologies.