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Updated: Mar 31, 2026

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering
Published on: November 5, 2018
Molecular weight-gyration radius relation of globular proteins: a comparison of light scattering, small-angle X-ray
Detlef-M Smilgies1, Ewa Folta-Stogniew2
1CHESS, Cornell University , Ithaca, NY 14850, USA.
Abstract:
The molecular weight-gyration radius relation for a number of globular proteins based on experimental light scattering data is compared with small-angle X-ray scattering data recently published by Mylonas & Svergun [J. Appl. Cryst. (2007 ▸), 40, s245-s249]. In addition, other recent experimental data and theoretical calculations are reviewed. It is found that the MW-Rg relation for the globular proteins is well represented by a power law with an exponent of 0.37 (2).
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