Linear Darier's disease: A case with bilateral presentation.

Area of Science:

• Dermatology
• Genetics
• Clinical Case Reports

Background:

• Darier's disease is an autosomal dominant genodermatosis.
• Characterized by hyperkeratotic papules on seborrheic areas, nail abnormalities, and sometimes mucosal lesions.
• Typically presents in younger individuals with pruritus.

Observation:

• An atypical case of Linear Darier's disease is presented.
• The patient was a middle-aged adult with a bilateral presentation.
• Lesions mimicked other dermatological conditions.

Findings:

• The case demonstrates a rare variant of Darier's disease.
• Linear Darier's disease can occur bilaterally in adults.
• Differential diagnosis included lichen planus, inflammatory linear verrucous epidermal nevus, and warts.

Implications:

• Highlights the importance of considering Darier's disease in atypical presentations.
• Atypical variants can pose diagnostic challenges, necessitating thorough evaluation.
• Broadens understanding of Darier's disease clinical spectrum and age of onset.