Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

11.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
11.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of Clinician Review Time and Confidence with Optical Coherence Tomography Digital versus Print-Based Workflows: A Pilot Observer Study.

Clinical ophthalmology (Auckland, N.Z.)ยท2026
Same author

Clinical Performance and Outcomes of a 20 000 Cuts-per-Minute, 25-Gauge, Beveled-Tip Vitrectomy Probe.

Journal of vitreoretinal diseasesยท2025
Same author

Clinical outcomes of a beveled tip, ultra-high speed, 25-gauge pars plana vitrectomy system.

BMC ophthalmologyยท2022
Same author

Outcomes of treatment with sirolimus for non-infectious uveitis: a meta-analysis and systematic review.

Clinical ophthalmology (Auckland, N.Z.)ยท2019
Same author

Comparison of surgical parameters using different lens fragmentation patterns in eyes undergoing laser-assisted cataract surgery.

International ophthalmologyยท2019
Same author

Comparison of Wound Sealability Between Femtosecond Laser-Constructed and Manual Clear Corneal Incisions in Patients Undergoing Cataract Surgery: A Pilot Study.

Journal of refractive surgery (Thorofare, N.J. : 1995)ยท2017

Related Experiment Video

Updated: Mar 31, 2026

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

3.3K

Posterior Uveitis.

Harvey Siy Uy, Ellen Yu-Keh, Pik Sha Chan

    Developments in Ophthalmology
    |October 27, 2015
    PubMed
    Summary

    Posterior uveitis, a leading cause of vision loss, is often treated with systemic corticosteroids or immunomodulatory therapy. Localized retinal pharmacotherapy offers a promising alternative to minimize systemic side effects.

    Area of Science:

    • Ophthalmology
    • Retinal Diseases
    • Inflammatory Eye Conditions

    Background:

    • Posterior uveitis is a significant global cause of ocular morbidity.
    • Systemic corticosteroids (CS) are the primary treatment but carry substantial side effects.
    • Immunomodulatory therapy (IMT) is an alternative but has toxicities and limited efficacy for some.

    Purpose of the Study:

    • To review posterior uveitis entities treatable with retinal pharmacotherapy.
    • To explore localized treatment options for posterior uveitis.

    Main Methods:

    • Discussion of common posterior uveitis conditions.
    • Focus on entities amenable to retinal pharmacotherapy.

    Main Results:

    More Related Videos

    Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
    07:40

    Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

    Published on: January 12, 2022

    6.4K
    Iris Fixation via External Pentagram Suturing
    05:22

    Iris Fixation via External Pentagram Suturing

    Published on: May 5, 2022

    2.0K

    Related Experiment Videos

    Last Updated: Mar 31, 2026

    Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
    10:33

    Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

    Published on: December 17, 2021

    3.3K
    Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
    07:40

    Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

    Published on: January 12, 2022

    6.4K
    Iris Fixation via External Pentagram Suturing
    05:22

    Iris Fixation via External Pentagram Suturing

    Published on: May 5, 2022

    2.0K
  • Intravitreal corticosteroid implants offer localized anti-inflammatory delivery.
  • Local administration may avoid systemic complications associated with CS and IMT.

    • Conclusions:

    • Retinal pharmacotherapy presents a promising approach for managing posterior uveitis.
    • Localized treatments aim to improve therapeutic levels while reducing systemic toxicity.