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Updated: Mar 31, 2026

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
Acute onset anterior uveitis after darbepoetin alfa infusion
Jonathan Li1, Stephen E Orlin2, Karen E Revere3
1Department of Ophthalmology, Scheie Eye Institute, 51 N 39th St, Philadelphia, PA, 19104, USA. jonli@mail.med.upenn.edu.
Abstract:
A 79-year-old female with a 2-month history of newly diagnosed myelodysplastic syndrome for which she received blood transfusion with darbepoetin alfa presented with bilateral anterior uveitis 1 day after her fourth transfusion. On exam, visual acuity was 20/20 in both eyes with biomicroscopy notable for conjunctival injection and anterior chamber cell and flare consistent with anterior uveitis. She had no systemic symptoms, no history of eye trauma, and no known infections. This case, along with prior reports in the literature, suggests that anterior uveitis may be an idiosyncratic complication of darbepoetin alfa therapy.
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