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Mesenteric Panniculitis Associated With Vibrio cholerae Infection
Grigory Roginsky1, Andrew Mazulis2, Jacob S Ecanow3
1Department of Medicine, Division of Gastroenterology, NorthShore University HealthSystem, Evanston, IL.
This study details the first case of cholera infection causing computed tomography (CT) findings similar to mesenteric panniculitis (MP). Treatment for Vibrio cholerae infection resolved the MP, suggesting an immune response.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Radiology
Background:
- Mesenteric panniculitis (MP) is a rare condition characterized by inflammation of the mesentery.
- Vibrio cholerae infection can cause severe gastrointestinal symptoms.
- The association between cholera and MP has not been previously reported.
Observation:
- A 78-year-old man presented with symptoms of acute Vibrio cholerae infection, including nausea, vomiting, abdominal pain, and watery diarrhea.
- Computed tomography (CT) revealed prominent lymph nodes and a hazy mesentery, findings consistent with MP.
- Stool cultures confirmed the presence of Vibrio cholerae.
Findings:
- This case represents the first documented instance of acute Vibrio cholerae infection associated with CT findings suggestive of MP.
- Following antibiotic treatment for Vibrio cholerae, the patient experienced complete resolution of the MP.
- Follow-up CT scans at 8 months showed complete resolution of the mesenteric changes.
Implications:
- The CT findings of MP in the context of Vibrio cholerae infection may represent an immunologically mediated reactive inflammatory disorder of the mesentery.
- This case expands the known spectrum of complications associated with Vibrio cholerae infections.
- Further research is warranted to understand the immunopathogenesis of this association.
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Assessment: