Fluoride Release from Hollow Silica Microsphere-Containing Dental Restorative Acrylate Resin

Hollow silica microspheres with mesoporous shells were prepared by the sacrificial template method. Hollow silica microsphere-containing acrylate resin-based dental restoration materials were prepared by using hollow silica microspheres as NaF reservoirs. Fluoride release performances from naked hollow silica microspheres, acrylate resin, and hollow silica microsphere-containing acrylate resin-based dental restorative materials in an artificial saliva were investigated. The results showed that hollow silica microsphere-containing acrylate resin-based dental restorative materials had higher cumulative fluoride release quantities and sustained fluoride release rates than traditional acrylate resin-based dental restorative materials. Fluoride release could be tuned by changing the mesoporous shell thickness of hollow silica microsphere.