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Related Concept Videos

Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
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[Treatment planning with functional MRI].

P Georg1,2, P Andrzejewski3,4, K Pinker3,5

  • 1EBG MedAustron GmbH, Marie-Curie-Straße 5, 2700, Wiener Neustadt, Österreich. petra.georg@medaustron.at.

Der Radiologe
|October 29, 2015
PubMed
Summary
This summary is machine-generated.

Advanced magnetic resonance imaging (MRI) techniques enable precise tumor definition for radiotherapy. Functional multiparametric MRI allows for targeted "dose painting," improving treatment outcomes and sparing healthy tissue.

Keywords:
Dose paintingFunctional magnetic resonance imagingImage guided radiotherapyIntensity modulated radiotherapyIon beam therapy

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Area of Science:

  • Oncology
  • Radiotherapy
  • Medical Imaging

Context:

  • Magnetic resonance imaging (MRI)-guided radiotherapy aims for high precision in treatment delivery.
  • New developments allow focused irradiation on tumors, sparing surrounding tissues.
  • Precise treatment planning and delivery necessitate equally precise tumor definition.

Purpose:

  • To explore functional multiparametric MRI for visualizing and quantifying biological processes.
  • To elucidate tumor biology and identify aggressive subvolumes resistant to radiotherapy.
  • To introduce the concept of "dose painting" for inhomogeneous tumor irradiation based on biological behavior.

Summary:

  • Dose painting, enabled by functional multiparametric MRI, is technically feasible.
  • This approach allows for selective treatment adaptations based on biological tumor characteristics.
  • Variable tumor responses necessitate individualized treatment plans for better outcomes.

Impact:

  • Clinical implementation of dose painting is expected to improve therapeutic outcomes.
  • Potential for higher local tumor control.
  • Enhanced sparing of normal surrounding tissues through targeted dose escalation.