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Surface Engineering of Pancreatic Islets with a Heparinized StarPEG Nanocoating
Published on: June 23, 2018
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Visible light-initiated interfacial thiol-norbornene photopolymerization for forming islet surface conformal coating
Han Shih1, Raghavendra G Mirmira2, Chien-Chi Lin3
1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Journal of Materials Chemistry. B
|October 29, 2015
Abstract:
A cytocompatible visible light-mediated interfacial thiol-norbornene photopolymerization scheme was developed for creating hydrogel conformal coating on pancreatic islets. The step-growth thiol-norbornene reaction affords high consistency and tunability in gel coating thickness. Furthermore, isolated islets coated with thiol-norbornene gel maintained their viability and function in vitro.
