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Updated: Mar 31, 2026

Procedure for Fabricating Biofunctional Nanofibers
Published on: September 10, 2012
Bottom-Up Instructive Quality Control in the Biofabrication of Smart Protein Materials
Fabián Rueda1,2,3, María Virtudes Céspedes3,4, Oscar Conchillo-Solé1
1Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, 08193, Cerdanyola del Vallès, Spain.
Abstract:
The impact of cell factory quality control on material properties is a neglected but critical issue in the fabrication of protein biomaterials, which are unique in merging structure and function. The molecular chaperoning of protein conformational status is revealed here as a potent molecular instructor of the macroscopic properties of self-assembling, cell-targeted protein nanoparticles, including biodistribution upon in vivo administration.

