Predicting cardiovascular disease from handgrip strength: the potential clinical implications

Area of Science:

• Gerontology
• Cardiology
• Public Health

Background:

• Handgrip strength is a validated prognostic marker for all-cause mortality, cardiovascular death, and cardiovascular disease.
• It serves as a crucial indicator of frailty and vulnerability in diverse populations.

Discussion:

• Handgrip strength measurement is particularly valuable in managing multi-morbidity, aiding in the identification of high-risk individuals.
• This simple assessment can guide clinical attention towards patients who may benefit from proactive interventions.

Key Insights:

• Low handgrip strength is associated with adverse health outcomes.
• The prognostic value is evident across various health statuses, including those with multiple chronic conditions.

Outlook:

• Ongoing research explores interventions (dietary, exercise, pharmacologic) to enhance muscle strength.
• Future studies will focus on the feasibility, sustainability, and clinical benefits of increasing muscle strength.