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Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds
Published on: August 25, 2013
Cell healing: Calcium, repair and regeneration
Alison M Moe1, Adriana E Golding1, William M Bement2
1Cell and Molecular Biology Graduate Program, Laboratory of Cell and Molecular Biology, 1525 Linden Drive, Madison, WI, USA.
Abstract:
Cell repair is attracting increasing attention due to its conservation, its importance to health, and its utility as a model for cell signaling and cell polarization. However, some of the most fundamental questions concerning cell repair have yet to be answered. Here we consider three such questions: (1) How are wound holes stopped? (2) How is cell regeneration achieved after wounding? (3) How is calcium inrush linked to wound stoppage and cell regeneration?
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