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Updated: Mar 31, 2026

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Identifying Infants and Toddlers at High Risk for Persistent Delays
Beth M McManus1, Cordelia C Robinson2, Steven A Rosenberg3
1Department of Health Systems, Management and Policy, Colorado School of Public Health, Children's Outcomes Research Group, Children's Hospital Colorado, 13001 E. 17th Place, MS B117, Aurora, CO, 80045, USA. beth.mcmanus@ucdenver.edu.
Most infant developmental delays resolve without early intervention (EI). Many children with mild or moderate/severe delays at 9 months showed no delay by 24 months, indicating developmental progress.
Area of Science:
- Child Development
- Developmental Pediatrics
- Longitudinal Studies
Background:
- Developmental delays identified in infancy often resolve by early childhood, but the persistence rates are not well-documented.
- Understanding these trajectories is crucial for identifying children who may need early intervention (EI).
Purpose of the Study:
- To examine the persistence of developmental delays from infancy to early childhood in a large, nationally representative sample of children who did not receive EI.
- To determine the likelihood of developmental delays resolving or worsening between 9 and 24 months of age.
Main Methods:
- Utilized data from a large (n ≈ 8700) nationally representative birth cohort study.
- Assessed cognitive and motor development at 9 and 24 months, categorizing delays as none, mild, or moderate/severe.
- Employed adjusted ordinal logistic regression to analyze the odds of persistent or worsening developmental delays.
Main Results:
- Approximately 24% of children exhibited cognitive delays and 27% motor delays at 9 or 24 months.
- A significant proportion of children experienced resolution of delays: 77% with mild and 70% with moderate/severe delays at 9 months had no delay at 24 months.
- Children with mild or moderate/severe cognitive or motor delays at 9 months had significantly higher odds (2.4 to 3 times) of worse developmental outcomes at 24 months compared to those with no delay.
Conclusions:
- Infant developmental delays are often transient and frequently resolve without formal early intervention.
- This study provides essential data on the natural course of cognitive and motor development in infants, highlighting the proportion of delays that resolve spontaneously.
- Findings inform our understanding of developmental trajectories and the need for targeted support for children with persistent delays.
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