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Status of gastric lavage in neonates born with meconium stained amniotic fluid: a randomized controlled trial

Lokraj Shah1, Gauri Shankar Shah2, Rupa Rajbhandari Singh3

  • 1Department of Pediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. lokraj94@gmail.com.

Italian Journal of Pediatrics
|November 1, 2015
PubMed

Insights

Gastric lavage (GL) is not necessary for vigorous neonates born with meconium-stained amniotic fluid (MSAF). This study found no significant difference in feed intolerance or vomiting between neonates who received GL and those who did not.

Area of Science:

  • Neonatal Medicine
  • Pediatric Gastroenterology
  • Clinical Trials

Background:

  • Neonates born with meconium-stained amniotic fluid (MSAF) may experience feed intolerance.
  • The incidence and management of feed intolerance in these infants require further investigation.

Purpose of the Study:

  • To determine the incidence of feed intolerance in vigorous neonates with MSAF.
  • To compare feed intolerance in neonates who received gastric lavage (GL) versus those who did not.

Main Methods:

  • A randomized controlled trial involving 500 neonates.
  • Participants were allocated to either the GL group (230 neonates) or the no lavage group (270 neonates).
  • Allocation was determined using computer-generated random numbers.

Main Results:

  • No significant difference in vomiting incidence between the GL and no lavage groups (8.7% vs 11.5%, p=0.305).
  • Feed intolerance showed no correlation with gestational age, gender, birth weight, or mode of delivery.
  • No complications were reported in the GL group.

Conclusions:

  • Gastric lavage is not indicated for vigorous neonates born with MSAF.
  • Current evidence suggests routine GL is unnecessary for this population.
Abstract

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