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First Bite Syndrome After Bilateral Temporomandibular Joint Replacement: Case Report
Nada Alwanni1, Mehmet Ali Altay2, Dale A Baur3
1Research Fellow, Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Case Western Reserve University, Cleveland, OH.
Summary
First bite syndrome (FBS) causes sharp parotid pain with eating. This report details the first known case of FBS following bilateral temporomandibular joint replacement surgery.
Area of Science:
- Otolaryngology
- Oral and Maxillofacial Surgery
- Neurology
Background:
- First bite syndrome (FBS) is characterized by parotid pain triggered by the initial bite of a meal.
- It is a known complication of parapharyngeal space surgery and other upper neck procedures.
- The pathophysiology of FBS remains poorly understood due to its rarity.
Observation:
- This report presents a unique case of FBS in a patient who underwent bilateral temporomandibular joint replacement.
- The patient experienced characteristic pain associated with the first bite of each meal post-surgery.
- This represents the first documented instance of FBS occurring after temporomandibular joint replacement.
Findings:
- The case highlights a novel association between temporomandibular joint surgery and the development of FBS.
- It suggests that procedures involving the temporomandibular joint may also predispose individuals to this condition.
- The findings expand the known iatrogenic causes of First Bite Syndrome.
Implications:
- This case broadens the differential diagnosis for post-surgical pain in the head and neck region.
- It may prompt further investigation into the neural pathways affected by temporomandibular joint surgery.
- Understanding this association could lead to improved patient counseling and management strategies for FBS.

