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Childhood injury after a parental cancer diagnosis
Ruoqing Chen1, Amanda Regodón Wallin1, Arvid Sjölander1
1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Insights
Children whose parents received a cancer diagnosis experienced a higher risk of injury, particularly in the first year. This risk increased if the parent also had a psychiatric disorder, highlighting a crucial public health concern.
Area of Science:
- Pediatric Health
- Oncology
- Psychological Impact of Illness
Background:
- Parental cancer diagnosis significantly impacts family well-being.
- Children are vulnerable to various risks following major family stressors.
- Understanding child injury risk in this context is crucial for support.
Purpose of the Study:
- To determine if parental cancer diagnosis increases children's risk of injury.
- To examine injury risk trends over time post-diagnosis.
- To identify factors, such as parental psychiatric comorbidity, that may modify this risk.
Main Methods:
- Swedish nationwide register-based cohort study.
- Comparison of injury hospital contact rates between children with and without parental cancer.
- Analysis of injury risk during the first three years and subsequent years post-diagnosis.
Main Results:
- Children with parental cancer showed a 27% higher rate of hospital injury contact in the first year (HR=1.27).
- This risk was elevated (HR=1.41) if the parent had a comorbid psychiatric disorder.
- The increased injury rate diminished over time but children with parental cancer had more repeated injuries (HR=1.13).
Conclusions:
- Parental cancer diagnosis is associated with an elevated risk of injury in children, especially within the first year.
- Comorbid parental psychiatric disorders exacerbate this risk.
- Findings underscore the need for targeted support and injury prevention strategies for families affected by parental cancer.
Abstract:
A parental cancer diagnosis is psychologically straining for the whole family. We investigated whether a parental cancer diagnosis is associated with a higher-than-expected risk of injury among children by using a Swedish nationwide register-based cohort study. Compared to children without parental cancer, children with parental cancer had a higher rate of hospital contact for injury during the first year after parental cancer diagnosis (hazard ratio [HR] = 1.27, 95% confidence interval [CI] = 1.22-1.33), especially when the parent had a comorbid psychiatric disorder after cancer diagnosis (HR = 1.41, 95% CI = 1.08-1.85). The rate increment declined during the second and third year after parental cancer diagnosis (HR = 1.10, 95% CI = 1.07-1.14) and became null afterwards (HR = 1.01, 95% CI = 0.99-1.03). Children with parental cancer also had a higher rate of repeated injuries than the other children (HR = 1.13, 95% CI = 1.12-1.15). Given the high rate of injury among children in the general population, our findings may have important public health implications.
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