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Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

Global Data Sharing in Alzheimer Disease Research.

Naveen Ashish¹, Priya Bhatt, Arthur W Toga

¹Laboratory of Neuro Imaging, Institute for Neuroimaging and Informatics, University of Southern California, Los Angeles, CA.

Alzheimer Disease and Associated Disorders

|November 3, 2015

Summary

Global Alzheimer's Association Interactive Network (GAAIN) facilitates Alzheimer disease data sharing. This infrastructure connects researchers worldwide, overcoming data access barriers to accelerate understanding of the disease.

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Area of Science:

Neuroscience
Medical Informatics
Public Health

Background:

Data sharing is crucial for Alzheimer disease research but faces significant capability limitations.
Existing research efforts are hindered by fragmented and inaccessible global Alzheimer disease data.

Purpose of the Study:

To discuss the benefits and impediments of Alzheimer disease data sharing.
To introduce a novel global infrastructure for linking and accessing Alzheimer disease data.
To present solutions for achieving large-scale, secure Alzheimer disease data sharing.

Main Methods:

Conceptualization of a global network infrastructure.
Development of a data-sharing model addressing key impediments.
Focus on data owner-sensitive solutions.

Main Results:

Introduction of the Global Alzheimer's Association Interactive Network (GAAIN).
GAAIN provides a secure network for accessing diverse Alzheimer disease data.
GAAIN integrates researchers, analytical tools, and computational resources.

Conclusions:

GAAIN offers a practical and promising approach to overcome Alzheimer disease data sharing challenges.
The network enables enhanced global research collaboration for Alzheimer disease.
GAAIN promotes data owner-sensitive solutions for secure data utilization.