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Updated: Mar 30, 2026

Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
Published on: January 8, 2016
Controlled-Release System of Small Molecules Triggered by the Photothermal Effect of Polypyrrole
Hui Zhang1, Linfeng Xiong1, Xiaojuan Liao1
1School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, 200241, China.
Abstract:
In this paper, a novel synthesis of polyethylene glycol (PEG)-modified polypyrrole (PPy) nanomaterials is demonstrated by combining reversible addition-fragmentation chain transfer polymerization and oxidative polymerization. Dye molecules with a heat-labile linker are used as a model drug and covalently anchored onto the PEGlated PPy nanomaterials via "click chemistry." The strong absorption of such PPy nanomaterials in the near-infrared region endows the system excellent photothermal effect, which can be used not only as efficient photothermal agents for photothermal therapy but also good controllers of a drug-release system by retro D-A reaction.
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