Related Experiment Video
Updated: Mar 30, 2026

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
Procedural Pain Management in Neonates, Infants and Children
1Consultant Paediatric Anaesthetist with an interest in paediatric acute and chronic pain Sheffield Children's Hospital, Weston Bank, Sheffield S10 2TH.
Insights
Children, including neonates and infants, experience pain during medical procedures and require effective analgesia. Combined non-pharmacological and pharmacological methods, guided by evidence-based protocols, are crucial for managing procedural pain and preventing long-term effects.
Area of Science:
- Pediatrics
- Pain Management
- Neonatal Care
Background:
- Neonates, infants, and children experience pain during medical procedures.
- Untreated procedural pain can lead to short-term and long-term adverse effects, including pain sensitization.
- Effective pain management is essential for pediatric patient well-being.
Purpose of the Study:
- To review effective strategies for managing procedural pain in neonates, infants, and children.
- To highlight the importance of considering developmental changes in pain response and pharmacokinetics.
- To emphasize the availability of evidence-based guidelines for pediatric procedural pain management.
Main Methods:
- Review of non-pharmacological and pharmacological interventions for procedural pain.
- Consideration of developmental variations in pain perception and drug response.
- Synthesis of current evidence-based guidelines for pediatric pain management.
Main Results:
- Combined non-pharmacological and pharmacological interventions are most effective for procedural pain.
- Developmental factors significantly influence pain management strategies in neonates.
- Comprehensive guidelines exist to support effective pain management across pediatric age groups.
Conclusions:
- Effective procedural pain management in children requires a multimodal approach.
- Tailoring interventions to developmental stage is critical, especially for neonates.
- Adherence to evidence-based guidelines ensures optimal pain relief and minimizes potential harm.
Abstract:
Neonates, infants and children all feel pain and require analgesia for painful procedures.Many painful procedures are associated with medical interventions, including immunisation, heel lance, venesection, IV cannulation and dressing change.Untreated pain can have short and long term effects, including sensitisation to pain episodes in later life.A range of non-pharmacological and pharmacological interventions have been shown to be effective for procedural pain management in infants and children, and are most effective when used in combination.Developmental changes in pain responses, analgesic response and drug pharmacokinetics need to be taken into account when planning procedural pain management for neonates.Comprehensive evidence based guidelines are available to guide effective procedural pain management in neonates, infants and older children.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Parenteral Anesthetics: Overview
Analgesia and Pain Management
Skeletal Muscle Relaxants: Therapeutic Uses
Peripheral Artery Disease V: Postoperative Nursing Management
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

