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Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
[Clinical practice guidelines: Benign breast tumor--Aims, methods and organization]
V Lavoué1, X Fritel2, J Chopier3
1Service de gynécologie, CHU de Rennes, ER440, Oncogenesis, Stress and Signaling, labelisé Inserm, CRLCC Eugène-Marquis, université de Rennes 1, 35000 Rennes, France; Collège national des gynécologues et obstétriciens français, 91, boulevard Sébastopol, 75002 Paris, France.
Clinical practice guidelines for benign breast tumors (BBT) are now available. This French College of Gynaecologists and Obstetricians initiative addresses the lack of data for managing benign breast disorders.
Area of Science:
- Gynecology
- Oncology
- Clinical Practice Guidelines
Context:
- Limited data and guidelines exist for managing benign breast disorders, unlike breast cancer.
- Benign breast conditions require structured clinical management protocols.
Purpose:
- To establish comprehensive clinical practice guidelines for benign breast tumors (BBT).
- To provide healthcare professionals with evidence-based recommendations for diagnosing and managing BBT.
- To address the disparity in available guidelines compared to breast cancer management.
Summary:
- A committee appointed by the French College of Gynaecologists and Obstetricians (CNGOF) developed these guidelines.
- Expert selection, question compilation, and recommendation summarization were key processes.
- Recommendations are based on a thorough review of scientific data, with evidence levels defined by the French National Authority for Health (Haute Autorité de santé) rating scheme.
Impact:
- Aims to improve the management of benign breast tumors.
- Provides a standardized approach for clinicians dealing with benign breast conditions.
- Enhances patient care by offering clear, evidence-based treatment pathways.

