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Updated: Mar 30, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Postpartum psychological disorders: Screening and prevention after birth. Guidelines for clinical practice]
1Département de psychiatrie de l'enfant et de l'adolescent de l'Association de santé mentale du XIII(e) arrondissement de Paris, 76, avenue Edison, 75013 Paris, France; Unité Inserm 669, UMR-S0669, universités Paris-Sud et Paris Descartes, 97, boulevard du Port-Royal, 75679 Paris cedex, France.
Objectives:
Focusing on the mother's postpartum psychological and psychiatric disorders.
Method:
Bibliographic research carried out by the data banks and the recommendations of learned societies from the following French words translated into English: postpartum, perinatal, postpartum, breastfeeding, birth, weaning, peripartum, lactation, postnatal, mood disorders, anxiety disorders, depression, anxiety, psychosis. These keywords were combined with the following words: prevalence, incidence, recurrence, development, identification, scale, assessment, test, father, man, husband, partner, hormones, treatment, intervention, prevention, testing, therapy, medicine, medication, to prescribe, prescription.
Results:
The months following the birth are a transitional period, and psychological alterations concern all parents (LE2). It is more difficult in case of psychosocial risk factors (LE2). In situations of proven psychological difficulties, the impact on the psycho-emotional development of children can be important (LE3). Among these difficulties, postpartum depression is the most common situation. Given its prevalence (about 13 %) and because of its implications for the entire family, it's an important health issue (LE2). However, the risk is generally higher in the perinatal period for all mental disorders (LE3). Pregnancy and postpartum are periods favorable to develop links with health professionals. New parents are often looking for support to deal with the upheavals associated with the birth. The postpartum period is thus for clinicians a unique opportunity to address the mental, social and somatic aspects of the health of their patients (professional agreement). Early detection and treatment of mental disorders are essential for family functioning and parent-child relationship (professional agreement).
Conclusion:
The issue of screening and prevention of postpartum mental disorders is fundamental and requires involvement of all professional receiving parents and babies in the aftermath of the birth.
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