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Updated: Mar 30, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy
Peter Papapetrou1, Aashish J Kumar, Rudram Muppuri
1From the Department of Anesthesiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.
Abstract:
Chemotherapy-induced peripheral neuropathy is a debilitating side effect of chemotherapy, which manifests as paresthesias, dysesthesias, and numbness in the hands and feet. Numerous chemoprotective agents and treatments have been used with limited success to treat chemotherapy-induced peripheral neuropathy. We report a case in which a patient presenting with chemotherapy-induced peripheral neuropathy received an IV lidocaine infusion over the course of 60 minutes with complete symptomatic pain relief for a prolonged period of 2 weeks.
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