Interventions for Hirsutism
Esther J van Zuuren1, Zbys Fedorowicz2
1Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
Clinical Question:
What medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism?
Bottom Line:
Oral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.
Related Concept Videos
Atherosclerosis III: Management
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Hormonal Regulation
Hormonal Regulation
Irritable Bowel Syndrome III: Medical and Nursing Management
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...


