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Updated: Mar 30, 2026
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Screening for breast cancer with Breast-CT in a ProHTA simulation
Georg Ruile1,2, Anatoli Djanatliev3, Christine Kriza2,4
1Institute of Medical Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Bavaria, Germany.
Aims:
The potential of dedicated Breast-CT is evaluated by simulating its impact onto the performance of the German breast cancer screening program. Attendance rates, cancer detection and economic implications are quantified.
Methods:
Based on a prospective health technology assessment approach, we simulated screening in different scenarios.
Results:
In the simulation, attendance rates increase from 54 to up to 72% due to reduced pain. Breast cancers will be detected earlier while nodal positives and distant recurrences decrease. Assuming no additional cost, cost savings of up to €55 million in one screening period are computed.
Conclusion:
The simulation indicates that earlier cancer detection, fewer unnecessary biopsies and less pain are potential benefits of Breast-CT resulting in cost savings and higher attendance.
