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Updated: Mar 30, 2026
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Published on: May 10, 2024
Probing the Association of Pancreatitis in Inflammatory Bowel Disease
Arvind I Srinath1, Neera Gupta, Sohail Z Husain
1*Department of Pediatrics, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center (UPMC), and †University of Pittsburgh, Pittsburgh, PA; and ‡Department of Pediatrics, Weill Cornell Medical College and New York-Presbyterian Phyllis and David Komansky Center for Children's Health/Weill Cornell Medical Center, New York, NY.
Abstract:
Inflammatory bowel disease (IBD) has been increasingly diagnosed in children and adults. Similarly, acute and chronic pancreatitis are increasingly prevalent conditions with potentially devastating consequences. There is a growing body of literature linking these 2 conditions. The purpose of this review is to provide a comprehensive outline of the association between IBD and pancreatitis and to explore their putative pathophysiology. Based on the collective reports, 2 outstanding reasons for pancreatitis in patients with IBD are medications and IBD complications.
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Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
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