[Selected work-related nephropathies]
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Induction of Nephrotic Syndrome in Mice by Retrobulbar Injection of Doxorubicin and Prevention of Volume Retention by Sustained Release Aprotinin
Published on: May 6, 2018
Wojciech Wołyniec1, Marcin Renke2, Małgorzata Wójcik-Stasiak3
1Gdański Uniwersytet Medyczny / Medical University of Gdansk, Gdańsk, Poland (Klinika Chorób Zawodowych, Metabolicznych i Wewnętrznych / Department of Occupational, Metabolic and Internal Diseases). wwolyniec@wp.pl.
Abstract:
Infections, high temperature and many of the toxic substances can cause kidney damage. Acute kidney injury is a well known complication of some work-related diseases, e.g., lead intoxication. Chronic kidney disease can also be caused by some occupational factors. Three work-related nephropathies, in which causal connection with work has been proved, are discussed in this article. There are different risk factors of nephrolithiasis, lead nephropathy and silica nephropathy, but each of them can cause chronic kidney disease. Prevention of these nephropaties seems to be relatively simple. The principles of protection from the toxic effects of heavy metals and silica dust are very specific. The most important prevention of kidney stones is correct fluid intake. In addition to providing adequate quantities of drinking water, it is also important to educate exposed workers and assure enough rest breaks at work.
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