Related Experiment Video
Updated: Mar 30, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
Lactate as predictor of mortality in polytrauma
Andréia Diane Freitas1, Orli Franzon1
1Hospital Regional Homero de Miranda Gomes, Secretaria de Estado da Saúde, São José, SC, Brazil.
Background:
The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs.
Aim:
To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care.
Method:
A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117.
Results:
Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928).
Conclusion:
There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma.
