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Lactate as predictor of mortality in polytrauma.
Andréia Diane Freitas1, Orli Franzon1
1Hospital Regional Homero de Miranda Gomes, Secretaria de Estado da Saúde, São José, SC, Brazil.
Summary
Lactate clearance does not predict mortality in multiple trauma patients. This study found no significant relationship between lactate levels or their clearance and patient survival in the intensive care unit.
Area of Science:
- Trauma critical care
- Metabolic markers in critical illness
- Outcome prediction in intensive care
Background:
- Lactate is a byproduct of anaerobic metabolism, indicating oxygen availability.
- Lactate levels can serve as a marker in resuscitation and critical care.
- Monitoring lactate changes is valuable even in patients with stable vital signs.
Purpose of the Study:
- To investigate lactate clearance as a predictor of mortality in intensive care unit (ICU) trauma patients.
- To determine the prognostic value of lactate clearance in severe trauma cases.
Main Methods:
- Study included 117 multiple trauma patients admitted to the ICU after applying exclusion criteria.
- Data collected on patient demographics, injury types (cranial, abdominal), and Glasgow Coma Scale.
- Mortality assessed at 48 hours and overall (global mortality).
Main Results:
- The study population was predominantly male (87%), with a mean age of 32.4 years.
- Motorcycle drivers with severe head and abdominal trauma were common.
- No statistically significant correlation was found between lactate clearance and mortality (p=0.928).
Conclusions:
- Admission lactate levels and lactate clearance are not correlated with mortality in multiple trauma patients.
- Lactate clearance may not be a reliable prognostic marker for mortality in this patient cohort.
