Related Experiment Video
Updated: Mar 30, 2026

Traumatic Peripheral Nerve Injury in Mice
Published on: March 25, 2022
Use of tubulization (nerve conduits) in repairing nerve defects in children
Filippo Maria Sénès1, Nunzio Catena1, Jacopo Sénès1
1Department of Head and Neck, Microsurgery and Hand Surgery Unit, Orthopaedic and Traumatology Unit, Istituto Giannina Gaslini, Largo G. Gaslini 5, 16147 Genova, Italy.
Background:
Direct neurorrhaphy, nerve grafting interposition and neurotization are the options for nerve repair in children, whereas few reports about using nerve conduits (tubulization) are referred to pediatrics in the literature. The authors present their experience about nerve repairing by means of nerve tubes during the developmental age when the harvesting of nerve grafts and also vein grafts of adequate caliber for bridging nerve defects is difficult. A critical review of their case series offers indications for using nerve conduits in pediatrics.
Materials And Methods:
Fifteen patients were treated using the nerve tubulization; nine patients were affected by obstetrical brachial plexus palsy (OBPP) while six were suffering from peripheral nerve injuries (PNIs).
Results:
In patients suffering from OBPP, we observed 1 good, 3 fair and 5 bad results. In the PNI group, we observed 4 patients who had good results while only 2 had a bad outcome. No fair results were observed.
Conclusions:
In peripheral nerve repairing in children by using nerve conduits, the outcome has been widely effective even when dealing with mixed and motor nerve, thus nerve tubulization might be considered as an alternative to nerve grafting. Conversely, considering the uncertain result obtained in brachial plexus repairing, the conduits cannot be considered as a first choice of treatment in brachial plexus reconstruction.
More Related Videos
08:05Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap
Published on: November 3, 2017
07:13Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
Neurulation